# Summary of #hplusroadmap IRC Log (June 13, 2014)

The log contained minimal substantive discussion, but these points emerged:

* A paper on clinical development success rates for investigational drugs was shared, with a participant mentioning they were analyzing the pattern of worsening returns in pharmaceutical R&D to determine investment limits and opportunity size.

* A discussion about improving drug development efficiency included the suggestion to reframe the problem as "if our target is 1 new drug per $1 million, what would have to change to make the system this efficient?"

* A resource on "Using Python to Code by Voice" was shared, prompting a brief discussion about voice interfaces for programming.

* A wiki page documenting "things that have been done with custom DNA" was created, with the author noting they were compiling examples of both commercial and non-commercial applications of synthetic DNA.

* A participant shared information about rare codons in protein production, specifically how placing rare codons at the start of a sequence can increase protein production, with supporting research papers.

* Various resources were shared including photoresist datasheets, microscope adapters, and a list of genetically modified crops from Wikipedia.