# Key Points from ##hplusroadmap IRC Discussion

• Participants discussed microfluidic oligonucleotide synthesizer technology, with kanzure explaining that building such devices requires photolithography equipment (projector, SU-8, plasma bonding, PDMS, spin coater), but basic photolithography can be accomplished for under $1,000 without million-dollar machines.

• The conversation highlighted the value of in-house microfluidic prototyping capabilities even for venture-backed companies, as outsourcing fabrication involves prohibitively long turnaround times.

• Animal breeding discussions revealed a gap between available technology and industry practices: while DNA sequencing for dogs costs $100-200, the breeding industry still relies primarily on pedigree tracking rather than genetic analysis.

• A participant sought open-source software for tracking rabbit breeding populations that could calculate Coefficient of Inbreeding (COI), include photos, and allow access by multiple breeders.

• Scientific papers were shared on topics including RNA structure, beta casein variants, dog coat variation genetics, and DIY photolithography techniques, demonstrating the channel's focus on open scientific knowledge exchange.

• A biohacking village planning meeting was mentioned for what appears to be a security conference, with the participant noting potential security concerns about malware and device vulnerabilities in biohacking equipment.