# Key Points from #hplusroadmap IRC Discussion

• Participants explored nuclear miniaturization possibilities, discussing how plutonium with neutron reflectors could theoretically create reactors as small as 10cm in diameter, alongside alternative technologies like betavoltaics and optoelectric nuclear batteries.

• A significant advancement in DNA nanotechnology was highlighted, featuring a 350-fold cost reduction in synthesizing DNA staples for DNA origami, as reported by the Foresight Institute.

• The conversation covered molecular nanotechnology components, including "molecular hinges based around acetylene, ferrocenes that are bearing-like, helicenes that are spring-like," demonstrating ongoing interest in nanomechanical engineering.

• The GDB (Chemical Universe Database) was discussed as a valuable resource containing up to 970 million druglike small molecules that follow chemical stability and synthetic feasibility rules.

• Participants contrasted Ripple's consensus mechanism with Bitcoin's, noting that Ripple uses a voting system among trusted validators rather than proof-of-work, potentially making it more vulnerable to state intervention.

• The WikiHouse project was shared, featuring time-lapse construction videos of buildings made from CNC-cut plywood components, representing innovative approaches to open-source architecture and construction.

• Technical discussions about GPU architecture on the Raspberry Pi revealed the community's interest in accessing and programming specialized hardware despite proprietary limitations, including mentions of assembly-language FFT implementations.