# Key Technical and Conceptual Discussions from #hplusroadmap

• Researchers are advancing bioprinting techniques by growing teeth using 3D printed biopolymer scaffolds seeded with osteoblasts and stem cells, demonstrating successful implantation in mice.

• The channel discussed space manufacturing technologies including lunar replicating factories, molten oxide electrolysis, and techniques for 3D printing structures using Martian or Moon soils.

• Participants explored 3D modeling approaches, comparing voxel-based systems to more complex geometric representations, with technical discussions about subdivision surfaces, NURBS, and the Additive Manufacturing File Format's support for curved triangles.

• Novel 3D printing methods for zero gravity environments were examined, particularly two-photon laser curing in gels that could enable high-resolution free-floating structures despite higher power requirements.

• Biomaterials innovation was highlighted through examples like Shrilk, a compostable material inspired by insect cuticle made from shrimp shells and silk proteins that matches aluminum's strength at half the weight.

• The group shared resources for metabolic pathway mapping, including KEGG (Kyoto Encyclopedia of Genes and Genomes), with one participant working on Python programs to map drug delivery receptors.

• Technical discussions covered hardware random number generators (OneRNG), entropy sources, and the security implications of entropy depletion in cryptographic applications.