# Key Ideas from #hplusroadmap IRC Discussions

• Research on brain rejuvenation was discussed, including whether Valproic acid might help make neural changes permanent, with additional conversation about aging-related immune system deficiency and thymus atrophy.

• Participants debated the value proposition of storing one's own stem cells while young for future therapeutic use, with some arguing it represents a worthwhile investment based on cost-benefit analysis.

• Contrary to common belief about significant neuron loss with age, the group noted research showing total neuron count remains relatively constant throughout aging, though cell density and morphology may change.

• Curcumin from turmeric was highlighted as potentially beneficial for brain health due to its ability to cross the blood-brain barrier, with references to preserved neural density in populations with high curry consumption.

• The group explored blockchain and Bitcoin technologies as platforms for novel financial instruments, debating whether these represent truly innovative economic systems or simply new implementations of existing models.

• A critical discussion of biotechnology emerged, including the high costs of genome sequencing ($2,500-3,500), concerns about Illumina requiring physician approval for consumer access, and criticism of media outlets for overhyping capabilities of platforms like OpenTrons.

• Participants characterized the academic postdoc experience as "indentured servitude," where talented scientists spend years doing low-skill work with limited professional development opportunities.