# Key Points from #hplusroadmap IRC Discussions

• Researchers discussed magnetic nanoparticles conjugated to proteins that can trigger specific cellular signaling pathways, enabling magnetic control of ion channels, membrane receptor activation, and protein positioning within cells.

• Spacecraft navigation techniques using millisecond pulsars were highlighted as promising due to their stable rotation rates, small detector size requirements, power/mass savings, and wide distribution across the sky.

• The NIH 3D Print Exchange (3dprint.nih.gov) was identified as a valuable resource for 3D printable models of biological structures and scientific equipment, including NK cell lytic synapse F-actin and micromanipulators.

• Robert A. Freitas Jr.'s "Xenology" (www.xenology.info) was shared as a comprehensive study of extraterrestrial life, intelligence, and civilization, originally written in 1979 but continuously updated.

• A discussion on interstellar archaeology focused on methods for detecting Dyson spheres as potential evidence of advanced extraterrestrial civilizations, with reference to content from centauri-dreams.org.

• Participants debated Bitcoin terminology, noting that references to "51% of miners" represent a misconception and should instead reference hashrate distribution.

• The practical aspects of rabbit polyclonal antibody production were discussed, with participants noting that rabbit antibodies bind to protein A/G, making them preferable to chicken antibodies for purification purposes.