# Key Points from #hplusroadmap IRC Logs

• A technical discussion on theoretical minimum cell size established that free-living coccoid cells would require approximately 0.15-0.2 μm diameter, providing context for discussions about biological scale limitations.

• Participants debated biological versus engineered computational efficiency, with references to Drexler's "Nanosystems" suggesting that theoretical diamond-based nanomachines the size of eukaryotic cells could vastly outperform current supercomputers.

• The channel discussed Harry Potter and the Methods of Rationality (HPMOR), a rationalist fiction work by Eliezer Yudkowsky, with mixed opinions about the author's writing style and recent funding requests for projects including a "successor to Wikipedia/Tumblr."

• A technical conversation about quantum mechanics interpretations occurred, with particular focus on the Many Worlds Interpretation (MWI) and its merits as potentially the simplest explanation according to Ockham's razor principles.

• Participants shared practical resources on nootropics, including Reddit's nootropics subreddit and Longecity, in response to requests for cognitive enhancement recommendations that wouldn't trigger caffeine sensitivity.

• The group noted Peter Thiel joining Y Combinator, an event significant to the transhumanist and startup communities given Thiel's investments in longevity and futurist ventures.

• An innovative healthcare initiative called "The Drugs Still Work" was discussed, which matches unused medicine with patients in need, representing a novel approach to medication access.