# Key Points from IRC Conversation

• Researchers discussed advanced optical nanopatterning techniques that confine light to deep subwavelength dimensions, enabling the creation of 36nm features using much larger wavelength light (633nm and 325nm) through a photochromic film that becomes selectively opaque.

• A participant named genehacker described work on photoisomerizing materials that change shape when exposed to light, with the ambitious goal of creating a Stewart platform (a type of parallel manipulator) inside a 100nm cube.

• The group discussed Chematica, a sophisticated software/database that uses algorithms to predict synthesis pathways for molecules by analyzing 250 years of organic chemistry knowledge, though it appears to be unavailable for public download.

• Several users engaged in detailed technical discussions about microfluidics manufacturing techniques, including SU-8 photoresist applications, KOH etching, and spin coating methods for creating features at the 5-micron scale for DNA synthesis and cell sorting applications.

• Participants shared resources for DIY lab setups, including a comprehensive cost spreadsheet and plans for an open-source aluminum 3D printer, with ongoing work to create complete "buy these things and it works" guides for biohackers.

• The conversation revealed active development of open-source scientific tools, including an Arduino-based signal generator called "Tsunami" (which reached 50% Kickstarter funding in 36 hours) and an open-source DNA synthesizer project with associated photomask designs.