# Key Points from #hplusroadmap IRC Discussion

• Researchers shared advances in brain-computer interfaces, including a persistent BCI capable of operating a text-speller at 2.3-2.5 letters per minute, and soft curved electrode systems that can be integrated on the outer ear for non-invasive neural monitoring.

• The channel discussed several innovative biotech startups, including Pembient (bioengineering wildlife products to combat poaching), Standard Cyborg (waterproof 3D-printed prosthetics), and Industrial Microbes (engineering microbes to convert natural gas into chemicals).

• A BRAIN Initiative funding opportunity was highlighted, offering $300K grants specifically targeting early-stage research on large-scale recording and modulation in the nervous system, with emphasis on recruiting researchers from outside traditional neuroscience.

• Participants shared information about novel optogenetic technology enabling blue-light-induced physiological responses, demonstrating the channel's interest in cutting-edge applications of biomedical engineering.

• The Biohack Academy (biohackacademy.github.io) was mentioned, sparking discussion about the institutionalization of DIY biology and non-institutional scientific research.

• A new WebGL-based CAD tool called Onshape, developed by the original Solidworks team, was discussed as offering free access for small public projects, representing advances in accessible design tools.

• The group critically analyzed biotech venture capital trends, noting constraints in biotech startup formation due to limited funding sources and the increasing dominance of corporate venture capital.