# Key Points from #hplusroadmap IRC Discussion

• Kanzure proposed developing cryonics-compatible organisms through selective breeding of animals that can survive freezing and thawing, suggesting this approach could lead to human applications within 5-20 years.

• Participants debated whether fixing aging or developing viable cryonics would be achieved first, with some suggesting brain uploading might precede both, while others argued reversing aging might be simpler than successful cryonics resuscitation.

• The conversation explored the relationship between cryonics and interstellar travel, noting that long-duration cryonics spacecraft would be necessary for million-year journeys, especially if Earth's atmosphere becomes incompatible with human life.

• Technical challenges of cryopreservation were discussed, including ice crystal formation and the potential benefits of pressure manipulation during freezing, with reference to experimental evidence of dog kidneys surviving cryostorage.

• A philosophical debate emerged about consciousness and personal identity in the context of uploading or copying minds, with divergent views on whether a destructive upload would end personal experience or if copies could continue one's identity.

• Participants discussed future megastructures including the Aerovator (a transorbital structure for launching payloads) and Dyson spheres, debating whether stars are the most efficient fusion reactors for large-scale energy collection.

• Autodesk's "Project Cyborg" was highlighted as an initiative combining nano-scale synthetic biology simulation with macro-scale CAD systems to optimize material performance through automated parameter adjustments.