# Key Points from #hplusroadmap IRC Discussion (June 18, 2015)

• All Library Genesis (LibGen) mirrors were reported down, highlighting potential access issues to scientific literature and research materials.

• A significant organizational split occurred in German cryonics, with operations now focused on the Berlin-Dresden axis after what was described as a "hijacking" by the Temple of the Vampire group.

• Participants debated Bitcoin governance models, contrasting centralized "benevolent dictator" approaches with decentralized systems where users validate rules themselves rather than trusting authorities.

• Kanzure and CaptHindsight discussed detailed technical specifications for building an open-source Inkjet Microarrayer for DNA synthesis, including using Epson printheads, laser verification systems, and nitrogen-filled enclosures, with a target cost under $2,000 (versus $20k-$100k for commercial systems).

• The discussion highlighted the tension between using higher-quality machine components (ballscrews, linear bearings) versus more accessible "hobby-grade" parts, emphasizing the importance of repeatability and accessibility in open-source scientific equipment.

• A US government Request for Information seeking "Nanotechnology-Inspired Grand Challenges for the Next Decade" was shared, with suggestions for DNA synthesis, genome synthesis, and shape-predictable restricted-amino-acid protein synthesis as potential areas.

• Participants shared notable scientific papers, including a meta-analysis on the heritability of human traits based on 50 years of twin studies and research on "Automatic imitation of physically impossible movements."