# Summary of IRC Conversation (July 23, 2015)

* A user requested access to a scientific paper "Temporal Coding of Visual Space" from MIT Press, which was shared through sci-hub, demonstrating the channel's focus on open access to academic research.

* Discussion about DNA synthesis technology included detailed technical exchanges about solid-support gene assembly methods, with particular focus on using photocleavable linkers and inkjet printing to create oligos on slides or trays.

* The conversation explored the technical challenges of DNA synthesis automation, including methods for moving tiny droplets (using electrostatic forces or light), cleaving oligos with UV lasers, and the chemistry of bonding anchored oligos to free-floating ones.

* A user shared a Hacker News link about optimizing CRISPR with "sub-second searches on a 3 billion base genome," which prompted criticism that the developers had created an inefficient solution by not conducting proper literature research on existing reference alignment tools.

* The channel participants were actively documenting their DNA synthesis research on a wiki (diyhpl.us/wiki/dna/synthesis/notes/), showing the collaborative and open-source nature of their transhumanist technology development.