# Summary of IRC Log from July 24, 2015

* Discussion about the shutdown of Library Genesis (LibGen), a major repository of academic papers, due to mounting legal pressure, highlighting ongoing tensions between open access advocates and traditional academic publishers.

* Kanzure mentioned seeking chemistry expertise for DNA synthesis projects, specifically regarding material compatibility for reactions documented at http://diyhpl.us/wiki/dna/synthesis/notes/, linker chemistry for solid supports, and cleaving/relinking techniques.

* A conversation about scientific knowledge distribution emerged, with participants discussing the challenges of creating open peer review systems and using technologies like IPFS (InterPlanetary File System) to distribute academic papers outside traditional publishing channels.

* Kanzure expressed disappointment with current methods of organizing scientific progress, noting limitations of both human-readable papers and machine-readable formats, and referenced alternative approaches like Constructor Theory (http://constructortheory.org/) which encodes scientific concepts as graph transformations.

* Several interesting engineering and technology links were shared, including screw-drive vehicles, industrial machinery photography, and the Bagger 288 excavator, reflecting the channel's interest in advanced technological systems.

* Two research papers were referenced related to angiotensin IV-derived peptides and their effects on cognition and synaptic function, particularly their dependence on the hepatocyte growth factor/c-met system.