# Key Points from #hplusroadmap IRC Discussion (August 18, 2015)

• Researchers discussed novel approaches to brain-computer interfaces, including the potential of using hair follicles and scalp skin as underutilized sensory input channels, with suggestions for electrical stimulation, piezoelectric actuation, or air puffs to stimulate mechanoreceptors.

• A significant advancement in wireless neural interface technology was shared via a Nature Methods paper on "Wirelessly powered, fully internal optogenetics for brain, spinal and peripheral circuits in mice."

• Participants explored various tactile interfaces for information input, comparing bandwidth limitations of different mechanoreceptors (20-250Hz) and discussing ultrasound tactile displays as non-invasive BCI options that could generate vibratory sensations through modulated radiation pressure.

• The group analyzed privacy challenges in onion routing systems, highlighting vulnerabilities in central directories, route negotiation, and the potential for ISPs to match encrypted packets and unmix relay traffic.

• Synthetic biology topics were discussed, including plasmid replication methods and alternatives to Cre/lox site-specific recombination techniques for genetic engineering.

• The upcoming SENS Foundation conference was highlighted, featuring presentations on thymus organoids, exceptional human longevity, and "young blood for old brains" research, reflecting the community's focus on longevity science.

• Several YCombinator biotech startups were mentioned, including TetraScience (lab equipment software) and Klarismo (offering $300 MRI scans), indicating growing commercial interest in accessible health technology.