# Key Points from IRC Discussions

• The High Court of Australia's decision in D'Arcy v Myriad Genetics Inc [2015] HCA 35 was shared, representing a significant legal development in biotechnology patent law, particularly regarding gene patents.

• Researchers discussed directed mutagenesis as a promising target for artificial selection, exploring how cells might be induced to direct mutations to specific genomic regions beyond just genes.

• Advanced mechanical engineering was highlighted through a tensegrity hexapod motion platform built by Fraunhofer, capable of impressive movement and potentially 20g accelerations.

• Participants explored adapting solid-phase peptide synthesis and oligonucleotide synthesis techniques for inkjet-based DNA synthesis to create large DNA fragments, genes, or entire genomes.

• The term "transhumanism" was debated as potentially problematic and alienating, with suggestions to use alternative terminology like "life optimization" to better communicate technological enhancement without negative connotations.

• Longevity research advancements were discussed, including startups working on senescent cell clearance (Oisin Biotech) and clearance of metabolic waste products contributing to atherosclerosis (Human Rejuvenation Technologies).

• A philosophical thread explored how poor philosophical frameworks can severely impede practical work, with participants noting that "really bad philosophy translates into being really bad at getting things done."