# Key Points from #hplusroadmap IRC Discussion

• A debate occurred about whether enzymes can be considered mechanosynthesis, with gene_hacker arguing it's "a bit of a stretch" while others considered the comparison valid in the context of molecular manufacturing.

• Kanzure shared research on spinal cord fusion through the "Gemini" protocol and the HEAVEN (Head Anastomosis Venture) project, which appears to be related to head transplantation research.

• FourFire described an ambitious long-term project (estimated 17+ years) to develop a tool using genetic algorithms and molecular dynamics to design proteins with specific functions, including DNA repair mechanisms and oxygen storage in human cells.

• Kanzure expressed skepticism about using genetic algorithms with molecular dynamics software for protein design, noting that "there are physical forces involved that are still not modeled in molecular dynamics software," and shared educational resources on protein engineering.

• A brief discussion of nootropics included observations that modafinil/provigil is "much more subtle" than Adderall and potentially suitable for daily use while maintaining normal social functioning.

• The community showed awareness of being monitored, with kanzure sharing analytics showing approximately 3,932 log requests since October 11, and participants discussing the balance between open collaboration and privacy in transhumanist discussions.

• Participants acknowledged a significant "lurker" population who read logs but don't actively participate, and discussed the implications of having their technical conversations monitored by both community members and possibly outside parties.