# Key Points from IRC Discussion (October 30, 2015)

• Participants debated early applications of molecular nanotechnology, weighing whether to prioritize high-impact applications versus technically feasible ones, with NV-diamond quantum computers identified as a promising early application of nanofactory technology for improving quantum system simulations.

• The discussion evaluated DNA origami as a potential pathway to advanced molecular manufacturing, with some expressing skepticism about its precision compared to other approaches, while others described using AFM (atomic force microscopy) with DNA origami tape containing nanocrystals for tooltip modification.

• Open hardware development was highlighted through several projects: Project IceStorm (documenting Lattice iCE40 FPGA bitstream format), open processor projects (PicoRV32, JCore, RISC-V), and the Novena open laptop with a 900MHz oscilloscope add-on.

• Software development tools were discussed, particularly deterministic debugging and replay tools including PANDA, rr-project, and Scribe, which allow developers to record and replay program execution for easier debugging.

• The conversation included technical references to CAD systems, mentioning a paper on adaptive sampling of parametric curves, and comparing B-rep and F-rep representation methods based on Adrian Bowyer's 2009 presentation.

• Participants mentioned "Mochii," purportedly the world's smallest production electron microscope, though one participant noted that only mockups were shown at a 2015 conference rather than a functioning device.