# Key Ideas from #hplusroadmap IRC Discussion

• Kanzure proposed an innovative DNA molecular ticker tape system for single-spike resolution recording, where DNA would be extruded through nanopores in cell membranes, potentially enabling evolution of cellular machinery based on its impact on DNA molecules.

• Participants debated rejuvenation mechanisms, comparing heterochronic parabiosis (connecting young and old circulatory systems) versus plasma injections, questioning whether stem cells are necessary for rejuvenation or if circulating factors alone can provide benefits.

• Current VR glove technology was criticized for significant limitations including lack of mechanical feedback and high latency (40-60ms), making them unsuitable for precision applications like typing.

• Andy Lo's "collateralized Biomedical R&D bonds" model was discussed as a potential solution for long-term research funding, proposing a $30 billion megafund for cancer research with applications to other technologies requiring 15-25 year funding horizons.

• The "Plutocratic Proposal" was shared as a framework for funding large-scale biomedical research through bonds sold to pensions, institutions, and the public, representing an innovative approach to financing transformative research.

• A speculative discussion emerged about enhancing human bodies with springs and shock absorbers, prompted by a paper on structural hydraulic shocks in bones, with debate about whether carbon fiber springs might outperform natural feet.