# Key Points from IRC Log (Nov 24, 2015)

• Discussion on cryoprotectant resistance selection methods, suggesting gradual increase of cryoprotectant concentration over generations rather than selecting for organisms that survive full doses immediately, with the observation that "you don't evolve to survive > 50% bloodloss."

• Oxygen microbubble technology was discussed as a medical intervention, with links to research on lipid-based oxygen microbubble emulsions that can temporarily oxygenate blood (http://www.jove.com/video/51467/manufacture-concentrated-lipid-based-oxygen-microbubble-emulsions).

• Advanced microscopy techniques were shared, specifically "Lattice light-sheet microscopy" which enables 3D imaging of fast dynamic processes in cells and embryos at subsecond intervals, with applications across four orders of magnitude in space and time.

• Computational tools were discussed, including KLEE (for automatic generation of high-coverage tests for complex systems), and a visualization map of 1,089,837 scientific papers from arXiv (http://paperscape.org/).

• Updates on the "verb" project for computational geometry were shared, noting that Boolean Representation (BRep) features won't be available until Q3 2016, with work progressing on BRep splitting, volume/area calculations, tessellation and core data structures.

• A DIY electronics discussion covered using photocells as light-controlled resistors with PWM-controlled LEDs to create digital potentiometers, with applications for laser brightness control in photoresist exposure.