# Key Points from IRC Log

• A review of noninvasive glucose monitors revealed that most are considered "vaporware," with archels suggesting the focus should shift to developing long-term implants instead, sharing links to comprehensive reviews on the topic: http://www.mendosa.com/The%20Pursuit%20of%20Noninvsive%20Glucose,%20Fourth%20Edition.pdf

• Discussion of GlucoWatch, a failed noninvasive glucose monitor that worked only 75% of the time, required sensor changes every 13 hours at $7.50 each (approximately $5k/year), and had significant accuracy issues, especially at low glucose levels.

• Current glucose monitoring technology uses semi-implanted sensors where reagents degrade over time, though some users have hacked devices like Dexcom to extend sensor life from the standard 2 weeks to potentially 3 months using medical adhesives and custom software.

• A new approach to glucose monitoring from Tohoku University was shared (https://www.tohoku.ac.jp/en/news/research/non_invasive_measurement_of_blood.html) that measures inside the mouth, though participants were skeptical about whether this represents a breakthrough or more "vaporware."

• Streety raised the question of whether there would be a market for finger-stick based diagnostics beyond glucose and ketones, noting that ketone finger sticks are available for approximately $3 each.

• Kanzure shared information about ongoing CRISPR patent disputes and drama (http://www.latimes.com/business/hiltzik/la-fi-hiltzik-20160206-column.html) and a paper on Cpf1, a single RNA-guided endonuclease of a Class 2 CRISPR-Cas System.

• A discussion about creating online platforms for biohacking concluded that "spaces are irrelevant; what matters is creating the people," suggesting that the proliferation of forums doesn't address the core need for knowledgeable, experienced practitioners.