# Key Points from IRC Log

• A user inquired about open-source tools for converting PostScript (PS) to G-code, with pstoedit and potentially BRL-CAD tools being suggested as partial solutions.

• A discussion about DNA sequencing library generation focused on finding cheaper alternatives to expensive kits from Illumina and Agilent, with a suggestion to look into barcode generation techniques.

• Kanzure speculated about the potential value in failed clinical trial datasets, suggesting that side effects might be acceptable tradeoffs for cognitive enhancements like "perfect memory."

• Intracellular parasites were discussed as potential vectors for novel types of surface display in vitro selection/evolution, with the possibility of selecting for specific host-parasite interactions.

• A paper on synapse-specific plasticity was shared, highlighting how mRNAs localize to distal dendrites and synapses where their translation can be regulated by activity, making individual synapses (rather than entire neurons) the units of plasticity.

• A study titled "Eye movements reveal epistemic curiosity in human observers" was shared, though no details about its findings were discussed.