# Summary of IRC Log Discussion

• A user shared a link to a synthetic biology primer from ETH Zurich, asking about finding part II of the document, though another user responded that they weren't sure if it existed.

• Kanzure shared information about Designer Receptors Exclusively Activated by Designer Drugs (DREADDs), explaining how these engineered receptors can be activated by compounds like clozapine-N-oxide to induce neuronal bursting or silencing, with advantages and disadvantages compared to optogenetics.

• Research on Highly Superior Autobiographical Memory (HSAM) was discussed, highlighting a study of eleven participants who could recall vast amounts of autobiographical information spanning most of their lifetime without using practiced mnemonics.

• Several neuroscience techniques were mentioned, including targeted memory reactivation (TMR) in sleep using audio cues, and transcranial laser stimulation for cognitive enhancement using low-level laser therapy with infrared light.

• Kanzure noted the absence of studies combining optogenetics with sleep and memory consolidation research, suggesting a gap in the scientific literature.

• A user named pasky announced an open beta for a service called vize.it and requested feedback, to which kanzure suggested skipping image-related work in favor of "better things to be tinkering on."

• Information about cell-penetrating peptides (CPPs) was shared, describing them as short peptides that facilitate cellular uptake of various molecular equipment through either chemical linkage or non-covalent interactions.