# Key Points from ##hplusroadmap IRC Discussions

• The Brussels Declaration for Radical Healthspan Extension was debated, with participants discussing aging as a "cascading failure" mechanism that typically begins with a health-diminishing event and represents the most common cause of death.

• Research was shared showing that high-functioning individuals with Autism Spectrum Disorder process eye-related social cues less accurately and more slowly than neurotypical people, while performing normally with non-eye directional cues like arrows.

• An open beta retakeable IQ test called Mielik (mielik.fi) was introduced for quantified self practitioners to measure cognitive changes before and after interventions, though its countdown timer feature raised concerns about stress-induced performance impacts.

• The Open Source Seed Initiative (OSSI) was discussed as an alternative to patented seeds, with participants noting the contradiction in its explicit rejection of GMO components despite opposing restrictive intellectual property arrangements.

• Potential cognitive interventions for elderly people were explored, including neural growth factors like lion's mane mushroom and acetyl L-carnitine, with suggestions that promoting new synapse formation could address age-related cognitive decline.

• A developer described working on a 3D autorouter for microfluidics using MonoSAT (a satisfiability modulo theory solver), sparking discussion about its advantages over traditional VLSI routing approaches.

• The GitHub repository "keras-molecules" was shared, which converts discrete molecular representations to continuous ones for efficient chemical compound space exploration, though frustration was expressed about the need for "bruteforce learning" approaches due to limited access to organic transformation mechanism databases.