# Key Points from IRC Discussion on Transhumanism and Technology

• Researchers proposed using Bitcoin mining as an energy storage mechanism for power plants, converting excess electricity into Bitcoin value rather than wasting it, potentially offering greater efficiency than traditional energy storage methods.

• A significant neuroscience advancement was discussed regarding quantum-dot-coated nanopipette electrodes (15-30 nm tip diameters) that achieved the first intracellular voltage recordings from dendritic spines, revealing that back-propagating action potentials fully invade spines.

• The conversation explored autoimmune causes of psychosis, referencing a UK trial where 3% of people with first-episode psychosis showed antibodies attacking NMDA receptors, suggesting some cases may be immune disorders rather than purely psychiatric conditions.

• Participants critically examined "citizen science," arguing that the term problematically frames unpaid scientific work as civic duty while professionals receive compensation, and suggested directly asking non-professional participants about meaningful forms of compensation.

• Several innovative iGEM synthetic biology projects were highlighted, including systems for delivering siRNA to mouse brains, bacterial outer membrane biosensors, and a notable project from Cork developing a novel bacterial method of DNA detection as a potential cheaper alternative to PCR.

• The discussion addressed geoengineering research using calcite (CaCO3) aerosol particles for stratospheric solar management that might simultaneously reduce radiative forcing while increasing column ozone, potentially offering advantages over sulfate aerosols.

• Participants noted that while DIY biology has become more accessible with cost barriers dropping from millions to $1k-$10k, DNA synthesis remains a significant bottleneck for interesting projects, with one participant mentioning their acquisition of a DNA synthesizer.