# Summary of IRC Conversation (January 7, 2017)

* Discussion of Memacs, a tool that integrates with Org-mode to visualize digital life history, with a link shared to a related article about managing digital photographs (http://karl-voit.at/managing-digital-photographs/).

* Extensive exploration of genes and SNPs related to memory and cognition, including KIBRA/WWC1, SORCS1, FADS2, NRXN3, IMMP2L, CHRM2, GRIN2B, SEMA5A, and others, with kanzure later committing this information to the DIY wiki (http://diyhpl.us/diyhpluswiki/genetic-modifications/).

* Sharing of several academic papers on genetic factors affecting memory, including "Genome-wide analyses of working memory ability," "A genome-wide survey of human short-term memory," and "Genome-wide studies of verbal declarative memory in nondemented older people."

* Discussion of a gene network explorer tool at http://genenetwork.nl that allows visualization of gene relationships and interactions.

* Interesting finding shared about Rs11074779, a genetic marker located near HS3ST4 that may play a role in herpes simplex virus pathogenesis, with a potential connection to hippocampal function and memory loss.

* Brief discussion about life extension literature, with kanzure sharing a resource (http://diyhpl.us/~bryan/papers2/longevity/) and FourFire mentioning a Discord group gathering longevity researchers.

* Mention of selegiline (L-deprenyl), a MAO-B inhibitor, with jcorgan describing it as a "Trojan horse molecule" that tricks monoamine oxidase enzymes.