# Key Points from the ##hplusroadmap IRC Discussion

• Researchers discussed telomere regulation through the TZAP protein, highlighting ongoing interest in biological mechanisms of aging and longevity within the transhumanist community.

• Open-source microfluidic technologies like OpenDrop and DropBot were examined, with particular focus on novel methods for tracking and controlling droplets using feedback amplifiers, webcams, and light-controlled systems that use photoconductors.

• A critique emerged of diamond-focused molecular nanotechnology approaches, suggesting that biological pathways (using ribosomes and polymerases) have proven more successful in laboratory settings.

• Participants noted a concerning trend of pessimism among cryonics advocates and older transhumanists, criticizing their failure to develop actionable plans despite gaining access to significant funding sources.

• The discussion connected gaming communities (Minecraft, Factorio) with real-world manufacturing potential, suggesting these platforms could serve as gateways to physical manufacturing projects.

• Practical proposals included creating vacuum cubes for testing space technologies on Earth and leveraging open manufacturing concepts documented by Paul Fernhout and Eric Hunting.

• Technical discussions touched on machine learning developments (Keras integration into TensorFlow) and cognitive enhancement substances (pharmacological effects of huperzine A).