2015-12-14.log

--- Log opened Mon Dec 14 00:00:36 2015
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kanzurehmph00:41
erasmusthey were all way off topic tonight kanzure00:42
erasmusI have no idea how that happened.00:42
erasmusthis shit never happens in ##Neurofeedback00:43
ebowdenWhat happens in ##Neurofeedback?00:43
erasmusmostly offtopic stuff00:44
ebowdenWhy?00:44
ebowdenWell, I guess that's the case for a lot of chans.00:45
erasmuscause most ppl cannot afford the hardware or software to train00:45
ebowdenSo it makes sense.00:45
erasmusbut that is changing fast00:45
erasmusopenbci will have aboard out for $9900:46
ebowdenNeat.00:46
erasmuswhich will work with bioera00:46
erasmusand dry sensors are becoming affordable00:46
ebowdenI wonder if the effect of neurofeedback would be enhanced with drugs like 7,8-dihydroxyflavone.00:47
erasmus https://github.com/OpenBCI/Ultracortex/tree/master/Mark_300:47
erasmusI would just like to get off stims personally00:47
erasmusI'm looking forward to training w/o pastes and gels00:49
ebowden7,8-dihydroxyflavone is a TrkB agonist, I've not heard of it being a stim.01:14
erasmusI'll stick with amfonelic acid thx01:29
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ebowdenwtf01:33
ebowdenThat's a DRI 150% the potency of dextroamphetamine, it has a massive half life and horrid withdrawal.01:34
ebowdenWhy on earth would you think that'd be a good idea, yet the neurogenesis enhancing flavonoid is horrible.01:35
FourFireerasmus, I hope they make their 160k stretch goal01:46
FourFirewant to experiment with tDCS, but equipment for it is too expensive for trivial hacking01:46
rhaps0dyerasmus: lol01:50
rhaps0dyare you an european exchange programme?01:50
ebowden*horrible?01:55
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FourFireinvited user Alycius to this channel.02:04
AlcyiusHello02:05
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FourFireGreetings02:13
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fennug so much backlog02:41
fennebowden: what were the BDNF drugs you were taking that you believe reduced your need for sleep?02:42
ebowdenMy need, or need in general?02:44
ebowdenWell, it was those and the neurofeedback. Maybe.02:48
ebowdenMaybe it was the placebo effect.02:48
ebowdenMaybe the drugs only upregulate BDNF in animal models.02:48
fennok but what was it02:51
ebowdenBerberine, and the much pissier curcumin, it's oral bioavailability enhanced with piperine.02:54
ebowden*its oral02:55
fennhum ok i don't think curcumin altered my sleep at all02:56
fennwhat sort of neurofeedback did you do?02:57
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ebowdenSomething for concentrating on small objects, I think.02:58
ebowdenFenn, because very little of it gets in your bloodstream.02:58
fenni used to take piperine but then i decided i would rather have functioning enzymes03:00
ebowdenYou would still have functioning enzymes, just ever so slightly less of them.03:01
fenni thought enzyme inactivation (cyp3a4?) was the mechanism by which it increased curcumin bioavailability03:02
ebowdenI've heard multiple mechanisms proposed.03:03
fenna 1999 patent says the mechanism is unknown03:03
fennpiperine may enhance bioavailability of curcumin by 2000% in humans (which is a 20-fold increase, as 100% is just normal absorption),[18] most likely due to inhibition of glucuronidation by the enzyme UDP-glucuronosyltransferase in the liver and small intestine.03:04
fennPiperine has shown "anti-depression like activity" and cognitive-enhancing effects in rats.03:05
ebowdenNot sure if any of the mechanisms proposed have been tested even as of now, say, a cyp3a4 knockout generated and the bioavailability enhancing effects compared between that and wild type.03:06
fenn5-20 mg/kg for the rat depression study, seems like a very high dose03:07
fenntypical capsules are 10mg so i'd need to take like 50 capsules03:08
ebowdenYup. I just had it for enhancing oral bioavailability.03:08
ebowdenNot that.03:08
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ebowden+seen gaydude03:09
fennapparently there is some formula with some cubic term in it, for scaling up rat doses to human doses03:09
ebowdenOh, derp, wrong chan.03:10
ebowdenI just use the FDA conversion factor.03:10
fenn"FDA guideline provide conversion of animal dose to human dose on the basis of body surface area."03:10
fennwho is gaydude?03:10
ebowdenI have just as little idea as you.03:11
AlcyiusI'd assume a gay male03:13
gaydudemmmm, yes ^^, hello03:13
gaydudei dont know any of you either ...03:14
ebowdenHe asked me, so I replied.03:14
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fenni'd assume a troll from reddit03:15
gaydudehahahah, no ... , why you think that?03:17
fennbecause you first joined at exactly the same time as atomical03:18
fennbut you haven't said anything of substance03:18
gaydudemmmmmmmm03:19
gaydudei dont tend to speak, just watch03:19
ebowdenI mostly think about ears.03:24
ebowdenwww.atomicpetportraits.com/the-worlds-longest-ears03:25
jrayhawkhttps://www.ncbi.nlm.nih.gov/pubmed/21592990 iiiiinteresting03:27
jrayhawkthat would explain more of the anti-candidiasis effects of goldenseal03:29
ebowdenI take berberine, not sure why I'd take that impure herbal stuff.03:30
fennlol03:30
fenncan't we all just get along03:30
ebowdenI'm perfectly calm.03:31
AlcyiusCan't we get irrationally angry at each other /s03:31
AlcyiusOn a serious note, I do have a question03:31
fenna lot of people on both sides seem to think herbal medicine and pharmaceutical medicine are mutually exclusive03:32
fennbut i think the science developed to study herbal medicines are what led to pharmaceutical medicine03:32
AlcyiusI'm not as knowledgeable about this stuff as I'd like to be, so as an aspiring computer scientist, what stuff would you guys recommend I start looking into in terms of advancing transhumanism03:32
jrayhawkhttp://diyhpl.us/wiki/projects/proposals/03:32
fennalcyius it depends what you mean by transhumanism03:33
Alcyiusfenn, I'd agree with you there. My problem is that a lot of people think that herbal medicine is better than modern medicine, and reject any evidence that shows that their favored herbal remedies don't work03:33
fennstep 1) define the problem. step 2) solve the problem.03:33
AlcyiusFair enough03:34
fennin general i recommend studying technical topics rather than getting lost in identity philosophy03:34
AlcyiusHeh03:34
AlcyiusOne of my world civ professors started getting me in those philosophical conversations03:34
AlcyiusI find them a good diversion03:35
AlcyiusPlus he buys coffee for me and sometimes pizza so03:35
fennstudying philosophy gives you ammunition to win cocktail party arguments, but if you still die at the end is it worth it?03:35
ebowdenAlcyius, he may want to have sex with you.03:36
ebowdenI take berberine because it was as effective as metformin in a phase 3 clinical trial for type 2 diabetes, I don't care that it's from plants.03:36
Alcyiusfenn, I treat it more as a mental exercise than anything else03:36
Alcyiusebowden, he's married, and I'm not the only one there03:36
gaydudemmm, but dont opose if it goes further i think...  hehe03:37
fennmental exercises have been shown not to increase fluid intelligence (except perhaps n-back but there's only one paper verifying that and others are having trouble replicating results)03:37
jrayhawk(similarly, http://www.nature.com/labinvest/journal/v92/n7/abs/labinvest201275a.html )03:37
ebowdenAlcyius, doesn't exclude the possibility.03:37
AlcyiusFair enough, but he's not my type03:37
ebowdenIs he tall?03:37
AlcyiusYes03:38
AlcyiusWhy?03:38
ebowdenHow tall?03:38
ebowdenI am very gay.03:38
Alcyiustaller than me, but only slightly and probably only cuz I use a cane03:38
AlcyiusHe's also in his late 60s03:38
AlcyiusHe could be my grandpa03:38
ebowdenThey're gentler.03:38
gaydudelol03:38
Alcyius*sigh*03:38
AlcyiusThat does remind me though03:38
AlcyiusHas anyone written anything about intersections of transhumanism and hedonism?03:39
ebowdenSo, 6'1'? 6'3'?03:39
Alcyiusprobably 6'1"03:39
fenndavid pearce wrote a lot of stuff about abolishing suffering and increasing happiness...03:39
gaydudegoing back to your question, i also think that you should be reading more technical details03:39
AlcyiusYeah probably03:39
AlcyiusI need to deal with my depression before I can effectively do that enough though03:39
gaydudeu.u03:40
fennAlcyius: http://hedweb.com03:40
AlcyiusAlso, while philosophical discussions might not increase intelligence or be effective as a direct means to an end, it does give me insight on how to better defend my position towards laypeople03:41
gaydudemmm, i use to imagine intersections of transhumanism and hedonism when not feeling "ok"03:41
ebowdenAlcyius, shame. I like people to be taller than me, but sadly am 6'.03:41
AlcyiusI honestly prefer short and I'm kinda sad that I'm 5'11"03:42
ebowdengaydude, are you a top?03:42
fennalcyius the best thing you could do at the moment is go work for some silicon valley startup and make tons of cash and then use it to fund scientists03:42
AlcyiusCourse, given the ability to modify my body as I please, I'd end up a lot different than I am currently03:42
gaydudeebowden: i have the same problem, and im 6´ to03:42
Alcyiusfenn, I mean, obviously03:42
fennis that obvious?03:42
gaydudeheheheheh no, you?03:42
AlcyiusYeah kinda03:42
AlcyiusTbh, that is the current goal03:42
ebowdenBottom.03:43
AlcyiusMake a lot of money, invest it to reach FI/RE, then pursue research at a university/make donations for scientists/lobby in favor of transhumanist causes03:43
gaydudealmost ..03:43
fennalso by "scientists" i am definitely definitely not referring to any "AI safety" bullshit03:43
fennwhat is FI/RE?03:44
AlcyiusFinancial Independence/Retire Early03:44
Alcyiuswww.reddit.com/r/financialindependence03:44
ebowdengaydude, what do you mean by "almost"?03:44
gaydudemmmm, not sure03:45
gaydudeAlcyius, whats the first modification you want?03:47
AlcyiusTough call03:48
AlcyiusI'd really like eyes03:48
AlcyiusBut, on the other hand, I'm not a big fan of the sex layout of my current body03:48
AlcyiusI mean, I don't mind, but it could be more enjoyable03:48
AlcyiusDoes a vasectomy count as a modification?03:48
Alcyius(To be perfectly honest, I'm looking at an RFID implant currently)03:49
fennwhy do you want an RFID implant?03:49
Alcyiusfenn, convenience and personal intereste03:49
fennwhy not just get an RFID ring?03:49
fennor bracelet or whatever03:50
AlcyiusBecause I lose jewelry and such with incredible frequency03:50
AlcyiusEspecially my glasses03:50
Alcyiuscan't lose an RFID implant03:50
gaydudei also want a RFID03:51
fennit turns out fitbit can be used to do bluetooth identification i.e. unlocking an android phone03:51
gaydudemmmmm, you have to start somewhere03:51
AlcyiusInteresting03:51
AlcyiusI'm also interested in a magnet implant03:51
fennit clips on with a metal spring, i keep it on my pocket next to my pocket knife03:52
AlcyiusBut my current plans for modifying my body are a tattoo, an RFID implant, and a vasectomy, not necessarily in that order03:52
gaydudeabout magnets, cant they go out in strong magnetic fields? xD03:52
AlcyiusTo be honest, I'm probably not gonna get a magnet because I do too much work building computers03:53
AlcyiusAnd I don't want to take that risk03:53
fennit takes a large number of cycles in a very strong field to demagnetize a permanent magnet, so you'd have to be near a coil with a flux concentrator and hold your hand over it, which would probably be quite painful03:53
fennalcyius i thought the primary use case for the magnet implant was to do electronics troubleshooting03:54
Alcyiusfenn, isn't there an issue with becoming desensitized to the magnet's movement?03:54
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Alcyiusfenn, I'm not entirely sure, I haven't read up on it in a while03:54
AlcyiusIt might be, but on the other hand, I don't want to ruin equipment worth $100s03:54
AlcyiusUnless I get to where I can afford that03:55
fennwell you can feel wires with current flowing in them and hard drive heads moving03:55
AlcyiusOh yeah definitely, I've read testimonies03:56
fennmagnet implants are so small it would be impossible to mess up a hard disk with one, even if you touched it while it was operating03:56
Alcyiuswhat about RAM and processors though03:56
fennno03:57
AlcyiusOh ok03:57
AlcyiusIn that case I only have to worry about MRIs03:57
fennthe only thing that might be affected is magnetic credit card strips03:57
AlcyiusWhich, depending on my condition, may or may not be in my future03:58
fennyou don't have a debit card?03:58
AlcyiusI meant MRIs03:58
fennoh03:58
AlcyiusI have a debit card yes03:58
AlcyiusNo I have Visual Snow accompanied by severe cluster/pressure band headaches03:59
AlcyiusAka, my vision looks like it's through a TV screen with a bad connector03:59
fennmigraine with aura04:00
gaydudehahaha04:00
fennyes it's so funny04:00
Alcyiusanyways, I have an exam to get ready for04:01
fennhttps://en.wikipedia.org/wiki/Aura_(symptom)04:01
Alcyiusfenn, my condition is distinct from migraines with auras. It is a persistent, all-encompassing visual disturbance that's closer to a haze of static than an aura, and the headaches are not migraines, but are instead cluster headaches or pressure band headaches04:08
Alcyiushttp://eyeonvision.org/visual-snow.html04:08
Alcyiusanyways, I have to go. Wish me luck.04:09
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fennhttp://selfhacked.com/2013/11/14/my-review-of-lllt/ near infrared laser therapy increases reactive oxygen species and has an anti-inflammatory effect by hormesis04:31
ebowdenHow did he measure this? Was it blinded?04:32
fennhonestly i'm skeptical of his personal experiments but there are a lot of links to scientific journal papers04:33
fennif i'm reading this right it seems like it's a technological substitute for exercise04:33
fennhe says methylene blue does the same thing04:34
fennif this cytochrome-pumping ROS generating effect of infrared is true, it would break down some safety distinctions between infrared and ionizing radiation04:38
fennhum maybe methylene blue is just a mitochondrial antioxidant, i don't see the evidence for hormesis04:41
fennmemory enhancement in mice injected with 1mg/kg methylene blue04:43
fennreview article of memory enhancement and neuroprotective effects of methylene blue http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265679/04:44
fennhis recommended dose is 60 micrograms of methylene blue04:51
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fennbest effects at 15-30 micrograms methylene blue reported by multiple people05:03
fenn"I felt more driven to get things done, more focused and more irritable / less patient with people and less interested in how they were going to feel if I said certain things"05:04
fennthere was some muttering about it being an MAOI05:10
fenninsignificant MAOI effect in the sub-milligram dose range05:20
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Diablo-D3so what doe it do?05:38
fennmitochrondrial antioxidant, and/or mito-hormesis by way of reactive oxygen species production, or something else entirely05:48
fenn"more driven and more irritable and memory consolidation" sure sounds like increase dopamine though (effect of MAOI)05:49
Diablo-D3maybe I should look into it >_.06:15
Diablo-D3>_>06:15
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AlcyiusHello06:41
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AlcyiusFinished with my exam06:42
Alcyiuscan't wait for 11, want me some chipotle06:44
AlcyiusShame they refuse to use GMOs, but maybe with the whole E. Coli/Norovirus deal they'll move. Or just require their farmers to implement stricter hygiene requirements06:45
AlcyiusOk that's kinda weird, periodically freenode keeps giving me a huge list of everyone in the channel06:46
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JayDuggerGood morning.07:05
AlcyiusMorning07:05
Alcyiusevery 4 minutes....that's weird07:05
JayDuggerThank you for the links, fenn.07:11
bjonnhthat's us-centric07:15
JayDugger?07:16
AlcyiusWhat's us-centric?07:16
maaku_Alcyius: you're young, in college I take it?07:23
AlcyiusYeah07:23
maaku_studying computer science?07:23
AlcyiusI start my first major courses next semester07:23
AlcyiusRight now the extent of my knowledge is some linux and how to build computers, but I'm a fast learner07:24
JayDuggerThought so, fenn. LLLT similar to, but not same as, one of Dave Asprey's of gadgets.07:24
maaku_well make shittons of money and reach FI is generally the approach for someone with such leanings07:24
AlcyiusYeah that's the plan07:24
AlcyiusI've seen what bad financial planning does to people07:25
JayDuggerReach FI with a job you like, if possible.07:25
AlcyiusMy dad got laid off and after drug abuse and stuff he killed himself07:25
AlcyiusSo yeah07:25
maaku_my recommended strategy: learn as much as you can in college, study abroad, and focus on -building things- , something you'll do outside of class07:25
JayDuggerMy sympathies for your loss.07:25
AlcyiusEh it was years ago07:25
maaku_also I'm sorry for your loss07:25
AlcyiusThe insane therapist who tried to brainwash me into evangelical christianity did more harm than the actual death07:26
AlcyiusBut thank you07:26
kanzureAlcyius: http://diyhpl.us/wiki/transhumanism07:26
maaku_pick a field that intersects your interests and is hot, enter startup land with goal of FI by 5 years via exit, if 5-8 years out that's not looking possible, switch to highpaying big business (google, facebook, etc.) with >$200k salary, live ina a shoebox and FI early07:27
maaku_also, buy bitcoins :)07:27
AlcyiusAlso, may/may not be relevant, but I do have about 3 months of experience in mass spectrometry, though that was really a crash course07:28
maaku_I really wish there was a company I could say "go work there!" but sadly there isn't anything like that out there yet...07:28
AlcyiusMight be able to leverage that, but I learned that I hate it07:28
maaku_also avoid philosophy07:28
JayDuggerFailing start-up land, live below your means, stay out of debt, invest the difference, and wait.07:28
Alcyiusmaaku_: eh, I have connections I can leverage for job opportunities, so I'm not TOO worried07:28
kanzurewaiting is overrated07:28
JayDuggerAnd yes, buy bitcoins. :)07:28
JayDuggerVery overrated, but it works.07:28
AlcyiusMy biggest issue now is overcoming my crippling depression to do well in my classes07:28
kanzurehave you tried lobotomy?07:29
maaku_Alcyius: I mean there really isn't any company out there working on the transhumanist vision directly07:29
AlcyiusI heard that there's a lot of issues converting bitcoins back to USD07:29
Alcyiusmaaku_: I figured07:29
JayDuggerI think a lobotomy would make waiting easier.07:29
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AlcyiusYes, but a lobotomy would kill my ability to DO stuff07:29
AlcyiusSo I'm looking into more therapy/psychiatric medications07:30
Alcyiushttp://www.smbc-comics.com/index.php?id=207107:30
AlcyiusHeh07:30
JayDuggerI hope you find an effective treatment, but I know very little about it.07:31
AlcyiusI think I need to look outside SSRIs07:32
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bjonnhhttp://www.sciencealert.com/us-town-rejects-solar-farm-amid-worries-it-would-suck-up-all-the-energy-from-the-sun?perpetual=yes&limitstart=107:32
AlcyiusThe ones I've tried just made me more depressed07:32
Alcyiusbjonnh: I saw that earlier today07:32
maaku_Alcyius: not really (re: bitcoin/usd). not unless you are trying to convert $100m or something like that07:32
Alcyiusone of our old family friends recommended day trading, but I'm kinda iffy07:33
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AlcyiusI like a good diversified stock portfolio with stable long-term growth07:33
bjonnhwhat worries me is that nobody was able to explain to them?07:33
Alcyiusbjonnh: people can explain all they want07:33
AlcyiusThese are people who DON'T want to listen07:33
bjonnhmay be07:34
Alcyius"I've decided to associate all change with social decay"07:34
bjonnhwell it is at least as dumb as accepting any change because progress07:35
AlcyiusI plan on being a self-aware old man07:35
Alcyiuswell07:35
Alcyiushopefully not an old man but that's another topic of discussion altogether07:35
bjonnhself-aware?07:36
Alcyiusolder people are likely to identify all change with social decay, ie. "Kids these days syndrome"07:36
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bjonnhso making hypothesis that there could be social decay07:37
bjonnhhow would it be identified then?07:37
AlcyiusThat's an interesting question07:38
AlcyiusMore on the side of philosophy07:38
Alcyiusbut if you were aiming to identify social decay, you need to establish a reference point07:38
maaku_Alcyius: when you're older you'll understand07:38
Alcyiuspffft07:38
bjonnhI think many old people identify correctly social decay. It is decay of their social system.07:39
bjonnhdoesn't mean that something else was not growing at the same time07:39
AlcyiusYeah, but they also have flawed memories07:39
bjonnhand youngs lack experience07:40
AlcyiusAnd idealize a version of the past that never really existed07:40
bjonnhthat's just two different biased ways to look at life :p07:40
kanzurewhen did this channel get so grumpy07:41
kanzurewho do i need to ban07:41
bjonnhwho is grumpy?07:41
AlcyiusNow now07:41
AlcyiusLet's just take a moment07:41
AlcyiusAnd get irrationally angry at each other07:41
AlcyiusLike adults07:41
kanzurewhat does that have to do with anything? huh?07:42
AlcyiusIdk07:42
Alcyiusalso philosophical discussions about transhumanism do have value08:21
Alcyiusthey help you figure out how to better defend it to laypeople08:21
AlcyiusAnd while you could just wait for people who are against it to die off08:21
AlcyiusThat's a long haul08:21
maaku_Alcyius: that has no perceived value here08:23
maaku_don't ask permission or bother explaining yourself. just do.08:23
Alcyiusimproving popular opinion on transhumanism equates to more funding and less hostility towards research08:23
kanzurethat's just false08:23
maaku_only when you're going about it the wrong way08:23
kanzure"raise awareness"08:24
kanzureno amount of "awareness" is going to fix your inability to execute08:24
kanzure*raised awareness08:24
AdrianGawareness is cheap.08:27
AdrianGjust develop solutions and sell them.08:27
AdrianGthere is a billion people waiting for solutions they will pay for.08:28
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bjonnhAlcyius: the philosophy here is JFDI.09:19
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kanzure"Many lab tests - though not all - are effectively commoditized. There is little difference in quality, and the requisite supplies are widely available at low costs. X-rays have been used for medical purposes for literally over 100 years, and it's not very difficult to train someone to take an x-ray properly using modern equipment. (Actually interpreting the results of a test is a different matter). For tests which fall under these ...10:06
kanzure... categories, it will always be more expensive to obtain them in the US than in India, because the cost-of-living in the US is much higher, and paying people to actually perform the tests dominates the costs of the test itself."10:06
kanzure.title https://news.ycombinator.com/item?id=1073141510:06
yoleauxMy adventures in medical tourism | Hacker News10:06
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kanzure"SceneNet: Understanding Real World Indoor Scenes With Synthetic Data" http://arxiv.org/pdf/1511.07041v1.pdf10:13
Jawmarekanzure, the rigorous QC requirement for lab test makes it expensive10:15
Jawmareanyone can operate a HPLC machine, but to make sure that the data is 99% accurate...10:15
kanzureyes i'm sure there are also regulatory costs10:18
TMAin the czech republic the equipment costs and regulatory costs dominate, not the personal costs; the personal costs are almost negligible in comparison10:24
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vortusWell I mean, given enough time and a bit of know how you could put together your own lab http://www.ebay.ca/itm/Hitachi-L-7400-UV-Detector-HPLC-System-/271889055444?hash=item3f4dd9bed4:g:2gsAAOSw~OdVbiVG10:29
vortusThere are also lots of other means to determine purity than an HPLC system, but the accuracy is lack luster.10:30
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bjonnhJawmare: also the right technique must be used…10:36
bjonnhbecause HPLC is not always the best choice for purity10:36
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doclAlcyius: mass spectrometry stuff could have important applications in self-replicating / semi-replicating robotic systems.11:09
doclfenn was talking about that in http://gnusha.org/logs/2008-03-28.log11:09
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drethelinsup bros11:52
eudoxiahello11:52
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AdrianGman12:51
AdrianGis all this dust and detritus?12:53
AdrianGhttp://diyhpl.us/wiki/projects/proposals/12:53
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kanzureit's a wiki, edit the page dude.13:06
kanzurehere's a bunch of projects http://diyhpl.us/wiki/dna/projects13:06
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FourFireHey kanzure, are you around?13:58
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FourFirenevermind, I lost my train of thought :/14:36
xentrackanzure recommends amphetamine for that14:38
rhaps0dyWhaat.14:41
fenndelayed release amphetamine14:43
fenn"XR"14:43
rhaps0dyI mean, you should just have posted your train of thought.14:44
fennyeah IRC is a variable-latency medium14:44
fenndon't ask to ask14:44
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xentracfenn: did you see my note the other night about topology optimization and negative stiffness?14:48
fennuh probably not14:48
xentracwell, if giant-stiffness metamaterials can in fact be constructed using negative-stiffness kinematics, then topology optimization might discover this14:49
xentracespecially since compliance (1/stiffness) is the objective function that people most commonly optimize in topopt14:50
fenni doubt there's a direct path that leads through this wacky mechanism with a linear optimizer14:50
xentracthis doesn't seem to have happened, which might be because (a) existing topopt systems use a search strategy that's too lame to find it, (b) because it isn't in fact possible despite what I think, or (c) some other reason14:50
fenn(a)14:51
xentracforgive me for going all Yudkowsky here, but I'd say this is a certain amount of evidence in favor of both (a) and (b)14:52
fennit doesn't find preloading either, and that definitely works14:52
xentracthose two things are not unrelated actually14:52
fennthere's just no representation for springs under tension in the model they are using14:53
xentracwell, there is; it just isn't part of their solution space14:54
xentracthe two things are not unrelated because no construct has negative stiffness everywhere; that would violate conservation of energy14:54
xentraconly over a certain range of deformations can you have negative stiffness14:54
fennwhat about unstable near-degenerate matter14:55
fenntouch it and it coalesces into neutronium14:55
xentracsounds tasty14:55
xentracanyway, that might be an adequate explanation by itself for why those solutions haven't been found via topopt14:57
fennor those closed cell foams containing vacuum14:57
xentracone of the most studied negative-stiffness configurations is a "holey sheet"14:58
xentracan elastomeric plate with a square grid of round holes in it14:58
fennthat doesn't seem like it would have negative stiffness14:58
rhaps0dyxentrac: awesome name ^^14:58
xentrac.g negative stiffness holey sheet14:59
yoleauxhttps://www.math.leidenuniv.nl/scripties/BachBeentjes.pdf14:59
xentracin that case the foam is just open on the sides instead of being full of vacuum14:59
fennoh because one side moves up when you push the other sie down?14:59
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fennthis still doesn't seem like negative stiffness15:00
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fenn"the applied compression is now larger than the critical displacement and the sheet has buckled, resulting in large displacements"15:01
xentracit turns out to have both a negative-stiffness region and a Poisson anomaly15:01
fennso i guess according to this definition a simple cylindrical tube is a negative stiffness stucture when compressed axially15:01
xentracyes, buckling beams are a very common way to get negative stiffness15:02
fenntheir constant capitalization of Holey Sheet is distracting...15:03
xentracyes, it seems like a particularly non-proper-noun sort of term, doesn't it?15:04
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fennfig 1.2 is sufficient to explain this entire paper15:05
xentracwell, you can't really deduce the negative-stiffness region in fig. 1.3 from fig. 1.215:06
fennhttp://fennetic.net/irc/holey_sheet_compression_negative_stiffness.png15:07
xentracyes, I know which fig. 1.2 you mean ;)15:08
fennwell others might be reading this and it would be dumb to download a 16MB paper just for this image15:08
xentracoh, okay15:09
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FourFireso, I'm going to be staying within drunken crawling distance* of this event I'm attending in germany during the weekend15:42
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AdrianGkanzure: you are missing anything nuclear related on your page. idk why.16:40
AdrianGregulations?16:40
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nmz787_iAdrianG: certainly not regulation related16:53
nmz787_iAdrianG: but what would your suggested additions be?16:54
nmz787_iaren't there outer-space type examples (dyson sphere stuff, etc)?16:54
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xentrackanzure: what do you think of Martin Bogomolni?17:15
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erasmushttp://www.bbc.com/news/technology-28041743?mc_cid=05a117aea0&mc_eid=308670b4dd17:37
xentrachave any of you looked at Jacques Mattheij's windmill design?  he wrote a parametric CAD system and built his own CNC plasma cutting system as part of the project, then open sourced it all17:40
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AdrianGnmz787: laser isotope enrichment18:15
AdrianGbut im afraid that instead of regulations, that would land you in jail (at best)18:15
xentracmaybe that's why?18:17
AdrianGwell, on paper it will be some kind of regulations they will cite18:24
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xentracmaybe if you're worried that talking about this will "land you in jail (at best)" then you shouldn't talk about it18:50
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AdrianGtalking about things isnt illegal19:16
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juri_xentrac: another parametric cad system?19:30
* juri_ is designing motor mounts for here CNC/3d printer/pen plotter/laser cutter/highres camera/... in her fork of ImplicitCAD.19:31
kanzurexentrac: hard to say... i know a thing or two, but they are strange and hard to explain why i know those things.19:35
kanzuredidn't know about jacquesm's cad software.19:35
kanzureer, my other message was re: martin19:36
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xentracheh\20:01
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xentracjuri_: it looks mostly like a bunch of PHP scripts that output G-code and do some visualizations in GD20:04
xentracthis kind of thing:20:04
xentrac# step 'inwards' at edge of slot20:04
xentrac$instep = $diameter / 100;20:04
xentrac# step inwards at the 3-4 and 5-6 edges20:04
xentrac$instep2 = $diameter / 60;20:04
xentrac$filletsize = $diameter / 100;20:04
xentrache also wrote an interactive Python thing for designing windmill blade profiles20:07
AdrianGare there 3D scanners btw?20:08
AdrianG3d printers would be a lot more useful if you can 3D scan. I've got like a million things i want to 3D scan.20:08
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xentracyes20:12
xentracstructured light, photogrammetry, cyberware laser scanners, structure from motion, and touch-probe 3D scanners20:12
xentracalso more specialized systems like holographic and LIDAR systems20:13
xentracmaybe http://reprap.org/wiki/3D_scanning is a good place to start20:14
xentracthe interactive Python thing is too janky for me to get it running right now, which is a shame; it looks like it might have interesting insights into his thought processes20:14
xentrackanzure: most things that can be known about Martin are strange :)20:15
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kanzure /win 320:54
kanzurefeoifqijeroq20:54
justanotherusermore like /lose 320:57
justanotheruserheyooo20:57
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kanzure"Estimating the reproducibility of psychological science" http://www.sciencemag.org/content/349/6251/aac471621:08
kanzure"Mapping tree density at a global scale" http://www.nature.com/nature/journal/v525/n7568/full/nature14967.html21:08
kanzure"Shaping the oral microbiota through intimate kissing" http://microbiomejournal.biomedcentral.com/articles/10.1186/2049-2618-2-4121:11
kanzure"CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes" http://link.springer.com/article/10.1007%2Fs13238-015-0153-521:11
kanzure"The genome of cultivated sweet potato contains Agrobacterium T-DNAs with expressed genes: An example of a naturally transgenic food crop" http://www.pnas.org/content/112/18/584421:11
kanzure"An investigation of the false discovery rate and the misinterpretation of p-values" http://rsos.royalsocietypublishing.org/content/1/3/14021621:18
erasmusI like kissing21:19
erasmus:X21:19
kanzure"Sizing ocean giants: patterns of intraspecific size variation in marine megafauna" https://peerj.com/articles/715/21:22
kanzure"The Oligopoly of Academic Publishers in the Digital Era" http://journals.plos.org/plosone/article?id=10.1371/journal.pone.012750221:37
kanzuredunno what is going on here "Continuous liquid interface production of 3D objects" http://www.sciencemag.org/content/347/6228/134921:38
Diablo-D3WHAT ARE WE DOING21:38
Diablo-D3er sorry caps21:38
Diablo-D3why do keyboards even HAVE capslock >_>21:38
kanzurecapslock is for resisting against the downcase apocalypse21:39
Diablo-D3YES, WE SHALL NOW ALL SPEAK LIKE THIS21:39
Diablo-D3LOOK AT ME, I SPEAK IN A LOUD VOICE. ALSO, MY VOICE IS DEEPER FOR SOME REASON.21:40
justanotheruserɪɴᴅᴇᴇᴅ21:41
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bjonnhDiablo-D3: because some DBs were coded in uppercase only22:16
bjonnhfor efficiency reasons and readability22:16
bjonnhalso because it is easier when you type an uppercase title22:16
bjonnhwhich was common on typewriters and early word processors22:16
justanotheruserI must be daft. Is this a joke?22:16
justanotheruserHow does uppercase only increase efficiency22:16
Diablo-D3justanotheruser is death.22:16
bjonnhjustanotheruser: upper or lower22:17
bjonnhwhatever22:17
Diablo-D3bjonnh: and its been a LOOOOONG time since all caps was a thing in any sort of coding22:17
bjonnhsure22:17
Diablo-D3like, I may in fact be younger than that trend22:17
bjonnhbut why are the keys in this order?22:17
Diablo-D3and Im 32.22:17
Diablo-D3I think you misunderstood22:17
justanotheruserbjonnh: because they were optimized for typing speed22:17
Diablo-D3why on a modern keyboard are we keeping capslock22:17
bjonnhjustanotheruser: optimized for typing speed on mechanical typewriters22:17
Diablo-D3but getting rid of _useful_ shit like that 6 key block above the cursor keys22:17
justanotheruserDiablo-D3: you mean left-upper-control?22:18
bjonnhjustanotheruser: because it jammed the arms together if you were typing some characters together22:18
justanotheruserbjonnh: no, you're thinking of qwerty22:18
Diablo-D3justanotheruser: meh, I know people who swap it with esc22:18
bjonnhyes22:18
bjonnhand he was asking why do we keep old stuff22:18
bjonnhlike capslock…22:18
bjonnhhistory22:18
justanotheruseroh. Only lame people use qwerty22:18
Diablo-D3bjonnh: no, I was asking why not get rid of it instead of getting rid of keys _I want to use_22:18
bjonnhoh22:19
Diablo-D3like, my favorite keyboard? has _exactly_ the keys I want22:19
bjonnhsorry22:19
bjonnhwhat is your favorite keyboard?22:19
Diablo-D3a tenkeyless made with plate mounted cherry mx reds22:19
justanotheruserDiablo-D3: http://www.wasdkeyboards.com/22:19
bjonnhactually my capslock is mapped to ctrl22:19
bjonnhand ctrl to compose22:19
Diablo-D3gets rid of the numpad, keeps the cursor keys and the pgup/dn/home/end/ins/del block22:19
Diablo-D3and has no fucking media keys22:20
Diablo-D3and no fn key22:20
Diablo-D3and no other stupid goddamned shit22:20
Diablo-D3bjonnh: and yeah, a lot of people do that22:20
Diablo-D3emacs people remap control to capslock habitually22:20
justanotheruserwhat I would really like is custom printed key stencils so I can paint the keys black, then paint the proper key on using the stencil22:20
bjonnhwell I'm an "emacs people"22:20
bjonnhso it is not surprising22:20
bjonnhand I'm using bepo (kind of dvorak for french)22:21
bjonnhbut I can swing between qwerty, azerty and bepo22:21
bjonnhwhen I use other people computers22:21
bjonnhjustanotheruser: I tried that with different kind of paints, but none stayed22:22
Diablo-D3so wait22:22
Diablo-D3why the fuck would you need dvorak for any language?22:22
bjonnhbecause dvorak is optimized for typing speed22:23
Diablo-D3I thought the entire point was an optimized layout that works well for all western languages?22:23
bjonnhand the most used letters are different in all languages22:23
bjonnhnope french has a lot of accents for example22:23
Diablo-D3huh22:23
justanotheruserhttp://luke.dashjr.org/education/tonal/keyboard/dvorak-tonal.png22:23
bjonnhbut there are other differences22:23
Diablo-D3justanotheruser: dont link to lukejr's website >_>22:23
justanotheruserwhy not?22:23
justanotheruserhe has some interesting stuff22:24
Diablo-D3because hes an annoying trolllllllll22:24
bjonnhDiablo-D3: why?22:24
bjonnhoh22:24
Diablo-D3people call me a troll? no. no no no, he has me waaay beat22:24
Diablo-D3I troll when an opportunity arrises, someone superglued his troll switch in the on position22:24
bjonnhalso it seems that dvorak may not be optimal in term of speed22:24
Diablo-D3bjonnh: it depends22:24
bjonnhthat's what wikipedia page says22:24
Diablo-D3like22:24
Diablo-D3I have too much muscle memory as qwerty22:24
justanotheruserbjonnh: there are some close layouts that beat dvorak22:25
bjonnhbepo is really recent and was really optimized for that22:25
Diablo-D3it'd take me another 20 years of nothing but dvorak to catch up22:25
justanotheruserbut its just barely22:25
Diablo-D3_and also_22:25
bjonnhalso works really well for english22:25
Diablo-D3I like to think before I type22:25
Diablo-D3I type like a typical perlist22:25
bjonnhI'm typing mostly english now, and my keyboards have the middle row erased ;)22:25
Diablo-D3plus, plus22:25
justanotheruseryou wore off the color?22:25
bjonnhyep22:25
Diablo-D3getting dvorak consistently22:26
Diablo-D3just wont happen22:26
justanotheruserI had dvorak stickers, the homerow stickers left first22:26
Diablo-D3okay so22:26
justanotherusernow all I have left are the very outside stickers22:26
bjonnhI stopped writing on keyboards or stickers22:26
Diablo-D3I learned to type at a very young age22:26
Diablo-D3how do you learn to type by looking at the keyboard?22:26
bjonnhyep22:26
bjonnhI just kept the layout in front of me on a sheet of paper22:26
Diablo-D3like, literally, I _know_ when Ive pressed the wrong key22:27
Diablo-D3I can feel it22:27
bjonnhtook me a couple of weeks to get to 3/4 of my azerty speed22:27
Diablo-D3its why I hate typing on foreign keyboards22:27
Diablo-D3the feel is all wrong22:27
bjonnhtook a long time to get beyond 100% though22:27
* Diablo-D3 feels like hes the only one here who gets that22:27
bjonnhand like 5 years after, I sometimes forget where a specific key is22:27
Diablo-D3also, btw, whats the point of typing faster than 120wpm?22:28
bjonnhis that a troll attempt?22:28
justanotherusertranscribing?22:28
justanotherusercoding faster22:28
bjonnhchatting on irc…22:28
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Diablo-D3I'm not trolling22:29
Diablo-D3Also, re: qwerty vs any other layout.... games.22:29
Diablo-D3too many games just very badly screw this up22:29
Diablo-D3wasd is wasd no matter what your layout is, period22:29
justanotheruseryeah, it does suck22:30
bjonnh"whats the point of reaching/doing xxx" is usually not really productive as a comment22:30
Diablo-D3I dont care what letter comes out when you press wasd, its wasd22:30
Diablo-D3bjonnh: no, it is22:30
justanotheruseryou can map ctrl+9 to remap though22:30
bjonnhwell you can map dynamically22:30
bjonnhmost OSes/DE support that22:30
Diablo-D3bjonnh: its called wasting time optimizing something thats already fast enough22:30
Diablo-D3mapping dynamically gets weird22:30
Diablo-D3due to in game chat22:30
bjonnhwell I don't do games22:31
bjonnhI wonder why you could decide that xxx is fast enough for everybody22:31
bjonnhit is like saying that 640k will be enough22:32
Diablo-D3because the human mind generally can only process intelligible language only so fast22:32
bjonnhyou're making this up22:33
bjonnhsorry22:33
Diablo-D3am I?22:34
bjonnhyes22:34
bjonnhstenotypist reach easily over 200wpm22:34
Diablo-D3I mean, you can start using counter arguments such as those training programs that make you read super fast or whatnot22:34
bjonnhand can go far higher22:34
bjonnhno22:34
bjonnhI'm talking about real life stuff22:34
bjonnhlike typists for court22:35
Diablo-D3do _any_ of those programs work btw?22:35
bjonnhfor their creator that sell them? probably :p22:35
Diablo-D3and btw, a lot of stenographers still use shorthand22:35
bjonnhand?22:35
bjonnhI was just opposing real data to your argument "human mind generally can only process intelligible language only so fast"22:35
Diablo-D3just saying22:35
Diablo-D3bjonnh: well22:36
Diablo-D3first of all, stenographers are unique22:36
bjonnhwikipedia says: The average adult reads prose text at 250 to 300 words per minute.22:36
Diablo-D3and it also takes the entire concentration to record accurately that fast22:36
bjonnhI'll not pursue this conversation further22:37
Diablo-D3*their22:37
bjonnhyou are just trying to justify an argument that was not valid22:37
Diablo-D3bjonnh: Im talking about average people, I guess.22:37
Diablo-D3bjonnh: okay so, wait a second22:38
Diablo-D3if the average person can read 250-300 words per minute22:38
Diablo-D3the average novel has 250-300 words per page22:38
Diablo-D3and there are, say, 500 page novels22:38
bjonnhyou are then making the assumption that this speed can be sustained for 500 minutes, and that attention is constant when reading a book22:40
Diablo-D3well what Im saying is22:40
Diablo-D3that actually might be right22:41
bjonnhyeah 1p/min sounds about right for novel-reading22:41
justanotheruserso what you're telling me is I can pump out 2 novels a day if I get to 200WPM?22:41
bjonnhjustanotheruser: YES22:41
bjonnhstart now22:41
Diablo-D3bjonnh: because I regularly read novels in around 5-8h depending on the size22:41
Diablo-D3well, used to regularly22:43
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